Charles Dexter Ward's wife enlists the help of a private detective to find out what her husband is up to in a remote cabin owned by his family for centuries. The　　husband is a chemical engineer| and the smells from his experiments (and the delivery of what appear to be human remains at all hours) are beginning to arouse the　　attention of neighbors and local law enforcement officials. When the detective and wife find a diary of the husband's ancestor from 1771| and reports of gruesome　　murders in the area begin to surface| they begin to suspect that some very unnatural experiments are being conducted in the old house. Based on an H.P. Lovecraft“一段八音盒的诅咒，在这段音乐没有消失之前你是处于一种安全的状态，但是音乐声消失之后你必死无疑，时间大概是几天到一个礼拜不等，具体期限得看你运气了。”